methandienone 10mg

Methandienone 10mg – means of plant origin, obtained by the original technology of the aerial part terrestris contains steroidal saponins mainly furostanol type. It has a tonic effect and stimulates some of the functions of the reproductive system. In men, restores and improves sexual libido, erections lengthens. Stimulates spermatogenesis, increasing sperm count and motility. The mechanism of action of extract   is unknown. It is expected that the vast protodioscin compound is metabolized in the body to dehydroepiandrosterone , which has a beneficial effect on the immune system, the integrity of the cell membrane, erectile function and cholesterol metabolism. It is known that cholesterol is a precursor for the synthesis of steroids, inclusive , testosterone and estradiol, which explains the effect of lipid-lowering . Other active furostanol saponins, are part of the extract  is likely to modulate the effect of protodioscin.

Tribestan has hypolipidemic effect: reduces total cholesterol low density lipoprotein , and in men the effect is more pronounced, it does not affect the values of serum triglycerides  ( high-density lipoprotein).  The drug is extensively metabolized in the body . Constant protodioscin rapidly cleared from plasma and after 3 hour of his concentration is low. After the drug orally for 24 hours with a minimum number of allocated bile protodioscin – 2 to 4%. The urine does not set a measurable concentration of unchanged protodioscin. After a single intravenous administration Tribestan throughout the day with bile output of about 12-14%, the kidneys – 6-7% protodioscin.

 

Indications

  • infertility in men, due to idiopathic oligoastenoteratozoospermiey (decrease in the number and quality of sperm in the semen selected), surgery for varicocele (varicose veins of the spermatic cord testicle), immunological infertility;
  • erectile disfunction;
  • with dyslipidemia to reduce methandienone 10mg total cholesterol levels.

 

Contraindications
: Hypersensitivity to all the components of the preparation. Prostate adenoma. Severe cardiovascular and renal disease. Pregnancy and breast-feeding. Use of the drug is not recommended for children under 18 years.

Dosage and administration
Used in. For the treatment of sexual dysfunction in men: 1-2 tablets per day during meals. The duration of the treatment of erectile dysfunction – at least 40-50 days, infertility – 70-90 days. Dyslipidemia: 2 tablets three times a day. The course of treatment should last at least 3 months. Repeated courses – on doctor’s advice.

 

Side effects
May cause nausea, which takes place in dose reduction or temporary (2-3 days) cessation of the drug, allergic reactions.

Overdose
There are no reported cases of overdose Tribestanom.

Interaction with other drugs
Tribestan may potentiate the effect of diuretics and antihypertensive drugs.

Cautions Effects on ability to drive and work with machines methandienone 10mg does not affect the ability to drive vehicles and classes of potentially hazardous activities that require high concentration and psychomotor speed reactions.